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KMID : 0359420060240010037
Korean Journal of Sports Medicine
2006 Volume.24 No. 1 p.37 ~ p.43
Correlation of Risk Factors on the Acute Inflammatory Markers and BMI, Serum Cholesterol Levels
Byun Jea-Chul

Abstract
BAKGROUND: C-reactive protein (CRP), fibrinogen, albumin, and white blood cell (WBC) counts were used as the markers for acute systemic inflammation. Acute inflammatory markers in blood are associated with increased risk of coronary heart disease (CHD).

OBJECT: The purpose of this study was to verify the correlation of risk factors on the coronary heart disease and body mass index (BMI), serum cholesterol.

METHODS: None of them has any illness and use of any medication during the experiment. Sixty-one healthy males are participated (Teenager, n=27; Youth, n=22; Middle-age, n=12).

RESULTS: The present study showed that HDL-C level is higher in the teenager than youth and middle-age. LDL-C level is lowered in the teenager than youth and middle-age. A level of CRP in one of the inflammatory markers was higher in the middle-age than teenager, and a level of fibrinogen was higher in the youth than the teenager. The other variables, in this study showed that age, BMI and total cholesterol, LDL cholesterol levels were associated with an elevated inflammation factors in the blood vessel. Futhermore, a high levels of blood TC and LDL-C were a positively correlated with the CRP and fibrinogen levels

CONCLUSIONS: Age, BMI, TC and LDL-C were independently related to increase the CRP and fibrinogen in Korean teenagers and youth and middle-age. Consequently, it may increased a cause of coronary heart disease in Korean men.
KEYWORD
Cholesterol, HDL-C, LDL-C, CRP, Fibrinogen, t-PA
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